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. 2024 Sep 11;18:98. doi: 10.1186/s40246-024-00669-7

Table 2.

Number of families, cases, and controls, T2D prevalence, and the average of covariates in each scenario

Generation size Family type No. of families
(all cases; cases & controls; all controls)a
T2D prevalence (%) Sex Caseb Controlc Age (years) BMI (kg/m2)
All families All 3,780 (368; 1,235; 2,177) 23.00 Men 961 4,531 46 27.06
Women 1,249 5,077 45.35 28.57
Generation ≥ 1 All 2,189 (26; 1,098; 1,065) 20.87 Men 745 3,939 44.5 27.01
Women 956 4,211 43.88 28.32
Case/control 1,098 (0; 1,098; 0) 38.50 Men 724 2,074 45.2 27.42
Women 914 2,180 44.07 28.85

aNo. of families = the total number of families in each scenario; all controls = number of families in which all individuals are negative for T2D; cases&controls = number of families in which both diabetic (case) and non-diabetic (control) individuals are present; all cases = number of families in which all individuals are positive for T2D

bCase = the total number of positive individuals for T2D included in each scenario stratified by gender

cControl = the total number of negative individuals for T2D included in each scenario stratified by gender