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. 2024 Sep 11;18:98. doi: 10.1186/s40246-024-00669-7

Table 5.

Spearman’s correlation between polygenic risk scores (PRS) and genomic estimated risk values (GERV) or estimated risk values (ERV) obtained from full models (1) and (2)a in different scenarios

GERV (p-value) ERV (p-value)
All families All 0.220 (4.28e− 122) 0.196 (4.20e− 96)
Generation ≥ 1 All 0.219 (1.81e− 100) 0.196 (3.74e− 80)
Case/control 0.224 (1.40e− 63) 0.210 (3.14e− 56)

a Models (1) and (2) represents pedigree-based and genomic prediction models, respectively