Figure 1. GlcN decreases RMC growth and induces hypertrophy.
Mesangial cells were exposed to 0.5 or 5 mM GlcN for 4 days. On each day, the cells were collected, cell number was counted and total protein content was measured. Growth curves corresponding to cell number (expressed in 105 cells) (A) and total protein content (expressed in μg) (B) are shown. The total protein/cell number ratio is presented in (C), expressed in μg of protein/105 cells. Results are the means±S.E.M. for four independent experiments. (D) Microscopy phase images of cells under control conditions or cells treated with GlcN. *P<0.05 versus control.