Table 1.
Baseline characteristics in the FAS.
| Parameter | FASa (N = 600) |
|---|---|
| Demographics | |
| Age, years | n = 600 |
| Mean (SD) | 54.3 (12.9) |
| Median (IQR) | 55.0 (45.0–63.5) |
| Sex, n (%) | n = 600 |
| Male | 403 (67.2) |
| Disease characteristics and concomitant conditions | |
| Etiology of ESRD, n (%) | n = 485 |
| Diabetic kidney disease | 135 (27.8) |
| Primary glomerulonephritis | 188 (38.8) |
| Hypertensive renal disease | 77 (15.9) |
| Others | 91 (18.8) |
| Medical history, n (%) | N = 600 |
| Presenta | 599 (99.8) |
| Hyperkalemia | 360 (60.0) |
| Renal anemia | 490 (81.2) |
| Hypertension | 487 (81.2) |
| Hyperphosphatemia | 283 (47.2) |
| Diabetes mellitus | 119 (19.8) |
| Metabolic acidosis | 79 (13.2) |
| Hyperlipidemia | 75 (12.5) |
| Coronary artery disease | 78 (13.0) |
| Hyperuricemia | 61 (10.2) |
| Dialysis parameters | |
| Type of hemodialysis, n (%) | n = 599 |
| Hemodialysis | 529 (88.3) |
| Hemodiafiltration | 60 (10.0) |
| Hemoperfusion combined with hemodialysis or hemodiafiltration | 10 (1.7) |
| Vascular access, n (%) | n = 599 |
| Arteriovenous graft | 11 (1.8) |
| Central tunneled dialysis catheter | 17 (2.8) |
| Arteriovenous fistula | 567 (94.7) |
| Other (temporary catheter) | 4 (0.7) |
| Dialysis frequency, n (%) | n = 599 |
| Three-times weekly | 509 (85.0) |
| Two-times weekly | 35 (5.8) |
| Five times every 2 weeks | 55 (9.2) |
| Dialysate potassium concentration, mmol/L | n = 599 |
| Mean (SD) | 2.0 (0.1) |
| Median (IQR)b | 2.0 (2.0–2.0) |
| Hemodialysis duration, hours | n = 599 |
| Mean (SD) | 4.0 (0.2) |
| Median (IQR) | 4.0 (4.0–4.0) |
| Urea reduction ratio, % | n = 589 |
| Mean (SD) | 68.0 (9.70) |
| Median (IQR) | 70.0 (60.0–70.0) |
| Kt/V | n = 577 |
| Mean (SD) | 1.45 (0.496) |
| Median (IQR) | 1.38 (1.20–1.61) |
| Gradient between dialysate and serum potassium (mmol/L), n (%) | n = 596 |
| 0–<1 | 2 (0.3) |
| 1–<2 | 81 (13.6) |
| 2–<3 | 269 (45.1) |
| 3–<4 | 213 (35.7) |
| 4–<5 | 25 (4.2) |
| 5–<6 | 6 (1.0) |
| Hyperkalemia treatment | |
| Use of potassium binders, n (%) | n = 600 |
| Yes | 15 (2.5) |
| No | 585 (97.5) |
a
Medical history that occurred in ≥10% of patients are presented.
bRange: 2.0–3.0 mmol/L.
ESRD, end-stage renal disease; FAS, full analysis set; IQR, interquartile range; SD, standard deviation.