Figure 1.

Median age of HPV disease diagnosis in female and male patients with GATA2 haploinsufficiency. The y-axis represents the age, and the x-axis shows HPV disease progression to cancer to include initial HPV disease diagnosis, low-grade squamous intraepithelial lesion (LSIL), high-grade squamous intraepithelial lesion (HSIL), and HPV-related malignancy that includes either carcinoma in situ or carcinoma. Box plots depict females in light grey and males in dark grey. Median age and range by sex for each HPV disease category is as follows: HPV at 19 (6 – 53) years and 14 (3 – 40) years in females and males, respectively, LSIL at 27 (15 – 42) years and 32 (25 – 33) years in females and males, respectively, HSIL at 27 (18 – 59) years and 33 (33 – 40) years in females and males, respectively and malignancy at 33 (23 – 59) years and 36 (33 – 40) years in females and males, respectively.