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. 2024 Sep 11;15:7954. doi: 10.1038/s41467-024-52348-9

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024

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Fig. 3 — a Neutralizing antibody (nAb) titer against Spike (BA.1 strain) pseudovirus; (b) IgG binding antibody (bAb) concentration against Spike (BA.1 strain). The curves show the relative efficacy of three-dose mRNA-1273 vs. two-dose mRNA-1273. The dashed black lines are 95% confidence intervals. The green histograms are an estimate of the density of predicted-at-exposure antibody marker level in per-protocol boosted SARS-CoV-2 naive participants. The gray shadings indicate the middle 90% (5th percentile to 95th percentile) of this marker distribution.