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Suggested protocol of perioperative direct oral anticoagulants (DOAC) management. (•) means that DOAC can be administered same day if procedures damaging mucosa (biopsy, cold snare polypectomy, etc) were not performed. ((•)) means that DOAC can be administered 2 days after high-risk procedures if there are no risk factors of postprocedural bleeding and no symptoms/signs of postoperative bleeding. CrCl, creatinine clearance; AM, ante meridiem; PM, post meridiem.
