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. 2024 Sep 2;28(5):525. doi: 10.3892/ol.2024.14658

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Copyright: © 2024 Uchikura et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Effects of Fyn knockdown on carboplatin sensitivity in ovarian cancer cells. (A) Reverse transcription-quantitative PCR analysis showing a significant decrease in Fyn mRNA expression in cells treated with Fyn-specific siRNA compared to those treated with control siRNA, confirming successful knockdown. (B) Cell viability assays showed decreased viability following Fyn knockdown and treatment with varying concentrations of carboplatin (≥100 µM) compared to control cells. Data are expressed as the mean ± standard deviation. *P<0.01, **P<0.05 vs. siFyn or as indicated. si, small interfering.