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. 2024 Aug 28;9(36):37636–37649. doi: 10.1021/acsomega.4c01203

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© 2024 The Authors. Published by American Chemical Society

Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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FBR improves HFD-induced obesity in the mouse gut microbiota. Volcano plots showing significantly changed microbiome using altered microbiomes according to log fold change and FDR at p < 0.01. (a) Normal diet group vs HFD-induced mouse group; (b) HFD group vs RBR HD group; (c) HFD group vs ORLISTAT group; (d) HFD group vs FBR LD group; (e) HFD group vs FBR MD group; and (f) HFD group vs FBR HD group. Red dots signify features that are negatively enriched, indicating a downregulation or decrease in the experimental group compared to the control. On the other hand, green dots denote positively enriched features, which suggest an upregulation or increase in the experimental group relative to the control. ***p ≤ 0.001. All the data are expressed as the means ± SDs (n = 7).