TABLE 1.
Patient characteristics at entry into the studya
| Characteristic | Patient 1 | Patient 2 | Patient 3 |
|---|---|---|---|
| Age (yrs) | 46 | 46 | 35 |
| HLA class 1 haplotypes | A2 A24(9)/B51(5) B 62(15) | A2 A32/B12(44) B14/C8 | A11 A24(9)/B35 B51(5)/C4 |
| Risk factor | Homosexual activity | Homosexual activity | Homosexual activity |
| First HIV seropositivity (yr) | 1986 | 1986 | 1991 |
| Maximal viral load before HAART (copies/ml) | 59,000 | 48,500 | 73,000 |
| Nadir CD4 count before HAART (mm−3) | 236 | 456 | 211 |
| Duration of HAART before entry (mo) | 46 | 18 | 21 |
| CD4 count at entry (mm−3) | 674 | 920 | 511 |
| Viral load at entry (copies/ml) | <200 | <200 | <200 |
| Therapy at baseline | Nevirapine + d4T + 3TC | AZT + 3TC + indinavir | AZT + 3TC + indinavir |
a
d4T, stavudine; 3TC, lamivudine.