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. 2024 Aug 30;15:1430928. doi: 10.3389/fimmu.2024.1430928

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Copyright © 2024 Zhou, Watt, Mai, Cao, Li, Chen, Duan, Quan, Gingras, Rini, Hu and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histopathology of SARS-CoV-2 infection in the lungs of single-dose HD-Ad-FS immunized hamsters. (A, B) The presence of SARS-CoV-2 RNA in lung sections was detected with RNAscope in situ hybridization at 4 (A) and 14 dpi (B). Hematoxylin and eosin staining (H&E, 5th row) was performed with lung sections of the indicated conditions. Continuous lung sections were used for staining. Scale bars = 200 (grey bar) or 1000 (black bar) µm. Images are representatives of n=2 per group. Data represent one independent animal experiment with indicated biological replicates.