Extended Data Fig. 6. Neurotransmitter release in NE neuron culture.
a–d, Norepinephrine concentration in the supernate at different time of culture (a), from different density of neuronal cultures (b) and in iPSCs derived NE cells (c,d). Data are shown as mean ± s.d. n = 3 biologically independent samples for each condition. Significance was assessed by one way ANOVA (Sidak’s multiple comparisons test).* p<0.05, ** p <0.01. ns, not significant. e, Dopamine. concentration in the supernate collected in different conditions. Data are shown as mean ± s.d. n = 4 biologically independent samples. Significance versus control group was assessed by one way ANOVA (Dunnett’s multiple comparisons test). **** p <0.0001. ns, not significant. N.D., not detected.