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. 2024 Sep 10;44(9):BSR20240311. doi: 10.1042/BSR20240311

Figure 6. Histological analysis of inflammation in CIA rat synovium.

Figure 6

(A) The H&E staining shows decreased inflammation (pink color) in Clo-miR-14 treated (N=4) and in MTX (N=4) groups compared with NC (N=4) CIA (N=4), and HC (N=4) groups. The arrow depicts cells in the synovium (B) The graph represents the analysis of cell infiltration in the synovium of different rat groups, which was measured and found to be down-regulated in the Clo-miR-14 (N=3) treated group compared with the CIA (N=3), and NC (N=3) group. CIA, collagen-induced arthritis; H&E, Hematoxylin and Eosin; HC, healthy control; NC, non-specific miRNA pool control; MTX, Methotrexate; ns, *P≤0.05, ***P≤0.001.