Table 1.

Subject and sample characteristics

Characteristic	Median (range) or number
Sex
Male, n	275
Female, n	237
Age, years; median (range)	37 (18–89)
Risperidone daily dose (mg); median (range)	3 (0.5–12)
Risperidone and 9-hydroxyrisperidone measurements
In total, n	1565
Per subject; median (range)	2 (1–41)
Risperidone dosing frequency prior to sampling, n
One dose per day	789
Two doses per day	758
Three doses per day	18
Time between dose and sampling, hours; median (range)	13 (9–30)
CYP2D6 allele, n
*1	401*
*35	54
*2-rs5758550A	27
*2-rs5758550G	166*
*9	20
*10	23
*41	66
*3, 4, 5, or 6 (deficient alleles)	269
CYP3A4 allele, n
*1	939
*22	27
Not determined	58
NFIB allele, n
T	965
C	53
Not determined	6

*Two subjects contributed 3 alleles (i.e., *1/*1 xN, n = 1 and *2-rs5758550G/*2-rs5758550G xN, n = 1)