Table 2.
Patient No | TNM | Tumor Method | Mutation in tumor | VAF tumor | Found in saliva | VAF saliva (Mutant/ Total Reads) |
---|---|---|---|---|---|---|
1 | T4aN2cM0 | WES | CDKN2A: p.R80X | 0.476 | Yes | 0.032 (3/94) |
TP53: p.R248W | 0.513 | Yes | 0.013 (3/236) | |||
2 | T4aNxM0 | WES | KDM6B: p.263_264del | 0.158 | Yes | 0.057 (24/418) |
TP53: p.G108Vfs*14 | 0.667 | Yes | 0.018 (10/546) | |||
NSD1: p.S1229L | 0.202 | Yes | 0.004 (2/546) | |||
5 | T4N2bM0 | WES | TP53: p.R282W | 0.382 | Yes | 0.005 (3/550) |
9 | T3N0M0 | WES | TP53: c.782 + 1G > A | 0.636 | Yes | 0.038 (15/397) |
12 | T2N2bM0 | WES | TP53: p.Y205C | 0.622 | Yes | 0.008 (10/1324) |
13 | T4N0M0 | WES | CDKN2A: p.M53I | 0.300 | Yes | 0.022 (14/630) |
TP53: p.A86Vfs*54 | 0.083 | Yes | 0.015 (13/861) | |||
PIK3CA: p.K548N | 0.184 | Yes | 0.058 (16/275) | |||
4 | T2N1M0 | WES | DNAH7: p.S8L | 0.192 | No# | <0.004 (1/252) |
8 | T4aN1M0 | WES | TP53: p.R273H | 0.134 | No | <0.002 (0/574) |
6 | T4aN2bM0 | Panelseq | TP53: p.V157F | 0.950 | Yes | 0.034 (71/2098) |
7 | T2N0 | Panelseq | PTEN: p.Q171X | 0.543 | Yes | 0.008 (7/864) |
10 | T4aN0 | Panelseq | TP53: p.Q65X | 0.016 | Yes | 0.007 (12/1696) |
#The one mutant read in this saliva sample did not pass calling criteria.