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. 2024 Apr;151:None. doi: 10.1016/j.oraloncology.2024.106717

Table 2.

Summary of shared somatic mutations between tumor and saliva DNA.

Patient No TNM Tumor Method Mutation in tumor VAF tumor Found in saliva VAF saliva (Mutant/ Total Reads)
1 T4aN2cM0 WES CDKN2A: p.R80X 0.476 Yes 0.032 (3/94)
TP53: p.R248W 0.513 Yes 0.013 (3/236)
2 T4aNxM0 WES KDM6B: p.263_264del 0.158 Yes 0.057 (24/418)
TP53: p.G108Vfs*14 0.667 Yes 0.018 (10/546)
NSD1: p.S1229L 0.202 Yes 0.004 (2/546)
5 T4N2bM0 WES TP53: p.R282W 0.382 Yes 0.005 (3/550)
9 T3N0M0 WES TP53: c.782 + 1G > A 0.636 Yes 0.038 (15/397)
12 T2N2bM0 WES TP53: p.Y205C 0.622 Yes 0.008 (10/1324)
13 T4N0M0 WES CDKN2A: p.M53I 0.300 Yes 0.022 (14/630)
TP53: p.A86Vfs*54 0.083 Yes 0.015 (13/861)
PIK3CA: p.K548N 0.184 Yes 0.058 (16/275)
4 T2N1M0 WES DNAH7: p.S8L 0.192 No# <0.004 (1/252)
8 T4aN1M0 WES TP53: p.R273H 0.134 No <0.002 (0/574)
6 T4aN2bM0 Panelseq TP53: p.V157F 0.950 Yes 0.034 (71/2098)
7 T2N0 Panelseq PTEN: p.Q171X 0.543 Yes 0.008 (7/864)
10 T4aN0 Panelseq TP53: p.Q65X 0.016 Yes 0.007 (12/1696)

#The one mutant read in this saliva sample did not pass calling criteria.