TABLE 1.
Negative seroreactivity to LANA2 in patients with KS, PEL, and MCDa
Donor category | No. of sera | Result (no. seroreactive/total no.) from:
|
||
---|---|---|---|---|
Western blot with ORF65 | IFA with LANA1 | Western blot with LANA2 | ||
AIDS-KS | 4 | 4/4 | 4/4 | 0/4 |
Classical KS | 4 | 4/4 | 4/4 | 0/4 |
MCD | 4 | 4/4 | 4/4 | 0/4 |
PEL | 2 | 2/2 | 2/2 | 0/2 |
Blood donors | 4 | 0/4 | 0/4 | 0/4 |
LANA2 hybridoma clonesb | 2 | ND | ND | 2/2 |
MCD, multicentric Castleman's disease; IFA, immunofluorescence assay; ND, not done.
Clones CM-10A2 and CM-8B6.