Figure 4.

Diagnostic yield of SJPedPanel. A,In silico coverage comparison between SJPedPanel and WES using percent coverage of variants (SNV, indels, fusion, SV, and ITD) reported in the “Genomes for Kids” study (16). The last pair of bars with the gray background shows the combined percent coverage over “All” 485 variants. B, Diagnostic yield of SJPedPanel by sequencing of previously reported 113 cases. y-axis shows percentage of covered and detected variants by SJPedPanel over each variant type. The last pair of bars with gray background for “All” variants show combined detection rate. Numbers of reported driver alterations are indicated at the bottom of bars for corresponding variant types.