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. 2024 Aug 24;16(17):2953. doi: 10.3390/cancers16172953

Figure 2.

Figure 2

Enzalutamide-resistant prostate cancer cells have upregulation of ST6GAL1 and increased levels of α2,6-sialylated glycans. (A) SNA lectin immunofluorescence shows VCaPEnzR cells have increased levels of ST6GAL1 and α2-6 sialylation (SNA, the lectin from Sambucus nigra, recognises α2-6-linked sialylated N-glycans [91]). (B) SNA lectin immunofluorescence shows LNCaPEnzR cells have increased levels of ST6GAL1 and α2-6 sialylation compared to control LNCaP cells. DNA is stained with Hoechst. Scale bar = 200 µM.