Table 2. Mean log reduction c.f.u. ml−1 among ESKAPE pathogens after 1 h incubation with 16-PLL10.
| Susceptible reference strain | Resistant strain/isolate | ||||
| Bacterial species | Ref number | Log reductionc.f.u. ml−1Mean±SEM* | Ref number | Log reductionc.f.u. ml−1Mean±SEM* | |
| Tested at 0.25 µM | A. baumannii | 19 606 | 0.65±0.12 | CI 23AD06 | 1.17±0.22 |
| P. aeruginosa | 27 853 | 1.53±0.15 | 13 437 | 0.76±0.18 | |
| E. faecium | 7174 | 5.13±0.13† | 12 204 | 5.03±0.14 | |
| K. pneumoniae | 9633 | 3.05±0.14 | 2146 | 5.61±0.05† | |
| S. aureus | 25 923 | 2.42±0.66 | 43 300 | 2.23±0.18 | |
| E. cloacae | – | – | 13 405 | 0.62±0.14 | |
| Tested at 2.5 µM | A. baumannii | 19 606 | 4.49±0.39† | CI 23AD06 | 4.96±0.11† |
| P. aeruginosa | 27 853 | 4.65±0.10† | 13 437 | 3.70±0.49† | |
| E. cloacae | – | – | 13 405 | 4.60±0.33† | |
a a*Assays carried out in triplicate on three separate occasions. limit of detection of the assay reached for at least one replicate.
†Limit of detection of the assay reached for at least one replicate.