Table 3. Mean log reductions (c.f.u. ml−1) among clinical isolates after 1 h incubation with 16PLL10.
| 16PLL10concn | Species | Ref. no | Site | Underlying condition | Log reductionc.f.u. ml−1±SEM* |
| 0.25 µM | A. baumannii | 23AD06 | BAL | – | 1.17±0.22 |
| A. lwoffii | 22AD05 | Foot Ulcer | Diabetes | 3.81±0.10 | |
| E. cloacae | 23AD01 | BKA Wound | Diabetes/PVD | 0.30±0.10 | |
| E. faecium (VRE) | 23AD04 | Foot Ulcer | Diabetes/PVD | 3.01±0.65† | |
| K. oxytoca | 23AD11 | Foot Ulcer | Diabetes | 2.45±0.10 | |
| P. aeruginosa | 22AD01 | Ankle Ulcer | PVD | 1.30±0.12 | |
| S. aureus (MRSA) | 23AD02 | Necrotic Toe | Diabetes | 2.49±0.17 | |
| S. aureus (MSSA) | 23AD10 | Foot Ulcer | Diabetes | 3.22±0.55 | |
| S. dysgalactiae | 23AD09 | Foot Ulcer | Diabetes/Chemotherapy | 0.78±0.07 | |
| 2.5 µM | A. baumannii | 23AD06 | BAL | – | 4.96±0.11† |
| E. cloacae | 23AD01 | BKA Wound | Diabetes/PVD | 4.53±0.36† | |
| P. aeruginosa | 22AD01 | Ankle Ulcer | PVD | 5.53±0.05† | |
| S. dysgalactiae | 23AD09 | Foot Ulcer | Diabetes/Chemotherapy | 3.78±0.29 |
a *Values shown are the mean±SEM from assays carried out in triplicate on three separate occasions. Reaching limit of assay for some/all experiments at this concentration. BAL – Bronchoalveolar Lavage, BKA – Below Knee Amputation, PVD – Peripheral Vascular Disease
†Reaching limit of assay for some/all experiments at this concentration.
BALbronchoalveolar LavageBKAbelow knee amputationPVDperipheral vascular disease