Table 4. Minimum bactericidal concentrations (MBC) and selectivity indices (SI) for 16-PLL₁₀ and 25% TFA-16-PLL₁₀ against antibiotic-susceptible and resistant bacteria.

	Bacteria name	Ref no./isolate	16-PLL10	16-PLL10	TFA-16-PLL10	TFA-16-PLL10
			MBC(μM)	SIIC50/SIMHC*	MBC (μM)	SIIC50/SIMHC*
Susceptible strains	A. baumannii	ATCC 19606	20	23.5/32	20	14.3/32
	E. faecium	NCTC 7174	5	5.9/8	5	3.6/8
	K. pneumoniae	NCTC 9633	25	29.4/40	20	14.3/32
	P. aeruginosa	ATCC 27853	10	11.7/16	10	7.1/16
	S. aureus	ATCC 25923	2.5	2.9/4	10	7.1/16
Resistant strains	A. baumannii	CI 23AD06	1.25	1.47/2	2.5	1.8/4
	E. faecium	NCTC 12204	10	11.7/16	10	7.1/16
	K. pneumoniae	ATCC 2146	20	23.5/32	>40	>28.5/>64
	P. aeruginosa	NCTC 13437	20	23.5/32	40	28.5/64
	S. aureus	ATCC 43300	2.5	2.9/4	10	7.1/16
All strains†	–	–	7.8‡	9.1/12.4	13.2‡	9.4/21.1

*Selectivity index calculated by dividing MBC by IC₅₀ value (0.85 µM - 16-PLL₁₀, 1.4 µM TFA-16-PLL₁₀) and MHC_5% (0.625 µM).

†Selectivity index calculated by dividing the geometric mean of MBC by IC₅₀ value or MHC value.

‡Geometric mean of MBC.

ATCCAmerican tissue culture collectionMBCminimum bactericidal concentrationMHCminimum haemolytic concentration that caused 5% haemolysisNCTCNational Collection of Type CulturesSI_IC50selectivity index based on IC₅₀SI_MHCselectivity index based on MHC