Table 1.

Parameters varied in the ABM.

Name	Description	Values (Baseline)	Source
$\mu$	CTL recruitment rate	2.5–25 (8) ABM CTL d−1	Calibrated
$h{a}_0$	Initial ratio of HA tumor cells to total tumor cells	0.05–0.95 (0.5) d−1	Estimated [33]
${\alpha }_{nt}$	Max ISF stimulated CTL proliferation rate	0.04–1.00 (0.15) d−1	Estimated [25,27,42]
${\delta }_{\mathrm{fast}}$	Fast kill rate	12–120 (48) d−1	Estimated [33]
$p_1$	Probability of fast killing for HA	0–1 (0.92)	Assumed
$p_2$	Probability of fast killing for LA	0–1 (0.33)	Assumed
m	CTL movement rate	1440–11,520 (2880) $\mu \mathrm{m}$ d−1	Estimated [33]
$\beta$	CTL Conjugation rate with tumor cells	12–96 (28.8) d−1	[33,43]
$a_{\mathrm{reach}}$	Immune stimulatory factor reach	60–200 (100) $\mu \mathrm{m}$	Estimated [33]
$r_{\mathrm{ISF}}$	ISF expression by LA tumor cells compared to HA tumor cells	0.1–0.9 (0.5)	Assumed [33]