Table 4.

Multivariate survival analysis in 32 osteosarcomas.

Characteristics	OS		RFS
	HR (95% CI)	p	HR (95% CI)	p
Age, years, ≥30 (vs. <30)			3.502 (1.221–10.045)	0.020
M category, M1 (vs. M0)	8.491 (1.622–44.448)	0.011
PAK4, positive (vs. negative)	6.888 (1.237–38.367)	0.028
PD-L1, positive (vs. negative)	2.978 (0.902–9.835)	0.073	5.512 (1.863–16.309)	0.002

OS, overall survival; RFS, relapse-free survival; HR, hazard ratio; 95% CI, 95% confidence interval. Multivariate survival analysis was performed with the potential prognostic indicators of osteosarcomas: age, TNM stage, T category, N category, M category, and the expression of PAK4 and PD-L1.