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Clinical pregnancy rates per OPU of donors of oocytes with <2.5% and ≥2.5% D4Z4 methylation. From the overall 56 OPUs, 17 OPUs had at least one GV oocyte with <2.5% D4Z4 methylation, while in 39 OPUs, no GV oocyte with <2.5% D4Z4 methylation was present. The clinical pregnancy rate per OPU was higher in donors of lowly methylated oocytes (6 of 17 OPU; 35%) compared to the group with ≥2.5% methylation (8 of 39 OPU; 20%). Please note that some of the 53 donors had more than one OPU.
