Table 4.
Predictors for postoperative seizures.
| Predictive Factor | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| OR (95% CI) | p-Value | OR (95% CI) | p-Value | |
| Age ≥ 68 years | 1.597 (0.841–3.033) | 0.153 | ||
| Male gender | 2.111 (1.111–4.009) | 0.023 | 1.863 (0.949–3.657) | 0.071 |
| WHO grade | not applicable | 0.566 | ||
| Non-skull base | 2.046 (1.072–3.906) | 0.030 | 1.546 (0.780–3.065) | 0.212 |
| Tumor size ≥ 4 cm | 0.974 (0.513–1.851) | 0.937 | ||
| Preoperative seizures | 2.241 (1.081–4.643) | 0.030 | 1.769 (0.814–3.844) | 0.150 |
| Preoperative KPS ≥ 80 | 0.933 (0.494–1.765) | 0.832 | ||
| Simpson grade | not applicable | 0.538 | ||
| Surgical complications 1 | 1.319 (0.601–2.895) | 0.490 | ||
| CNS infection | 0.396 (0.052–3.030) | 0.373 | ||
| Hydrocephalus | 1.657 (0.189–14.525) | 0.648 | ||
| Re-craniotomy due to swelling/bleeding | 1.404 (0.638–3.088) | 0.399 | ||
| Postoperative edema | 1.859 (0.836–4.136) | 0.129 | ||
| Sensorimotor deficit | 4.928 (2.492–9.745) | <0.001 | 4.490 (2.231–9.037) | <0.001 |
| Surgery duration ≥ 273 min | 1.295 (0.687–2.444) | 0.424 | ||
| Adjuvant irradiation | 1.543 (0.506–4.710) | 0.446 | ||
| Tumor progression | 1.690 (0.469–6.092) | 0.422 | ||
Significant p-values (p < 0.05) with OR (95% CI) in univariate analysis and multivariate analysis are bold. Abbreviations: OR—odds ratio; CI—confidence interval; WHO—World Health Organization; KPS—Karnofsky Performance Score; CNS—central nervous system. 1 Hydrocephalus, re-craniotomy and CNS infection.