FIG. 2.

Analysis of viral protein synthesis in COS-1 cells transfected with integrin subunit cDNAs. Cells were transfected with plasmids encoding integrin subunits as shown. Transfected cells were infected with FMDV type A₁₂ at an MOI of 10 PFU/cell and labeled between 4 and 18 h with [³⁵S]methionine. Cell extracts were analyzed by IP and SDS–10% PAGE as described in the text. The locations of viral structural proteins IP from infected and labeled BHK-21 cells (lane M) are shown on the left. con, nontransfected-infected cells (control).