Table 7.

SFTI-1-based selective inhibitors.

Target	Sequence	Ki
Trypsin	&1GRC(&2)TKSIPPIC(&2)FPD&1 (native SFTI-1)	100 pM [194]
Trypsin	GRC(&)TKSIPAIC(&)FPD	1.7 pM [195]
Trypsin	GKC(&)TKSIPPIC(&)FPD	2.0 pM [195]
Chymotrypsin	GRC(&)TXSIPPIC(&)FPD (X = 4-fluoro-L-phenylalanine)	30.0 pM [196]
Matriptase	KRC(&)TKSIPPRC(&)HPD (SDMI-3)	2.1 pM [197]
Plasmin	&1GRC(&2)YKSKPPIC(&2)FPD&1	50.0 pM [198]
KLK-4	&1GFC(&2)QRSIPPIC(&2)FPN&1	40.0 pM [199]
KLK-5	&1GYC(&2)NRSYPPEC(&2)FPN&1	340 pM [200]
KLK-7	&1GKC(&2)LFSNPPIC(&2)FPN&1	140 pM [201]
Furin	KRC(&)KKSIPPRC(&)F-NH2	490 pM [188]
Chymase	&1GRC(&2)QXSEPPEC(&2)FPD&1 (X = 4-chloro-L-phenylalanine)	1.8 nM [202]
Cathepsin G	&1GTC(&2)X1X2SDPPIC(&2)FPN&1 (X1 = norleucine; X2 = 4-guanidine-L-phenylalanine)	1.6 nM [203]