Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Guanidinylated aryl-2,5-dideoxystreptamine inhibitors of PCs [234].
| |||||||
| No. | Enzyme | ||||||
| Furin | PC6B | PACE4 | PC7 | LF | Trypsin | MT1-MMP | |
| Ki, nM | |||||||
| 1e | 6 ± 2 | 4 ± 1 | 25 ± 2 | 415 ± 14 | 1002 ± 19 | >200,000 | >200,000 |
| 1g | 12 ± 3 | 4 ± 0 | 41 ± 1 | 595 ± 47 | 1241 ± 36 | >200,000 | >200,000 |
| 1n | 46 ± 3 | 21 ± 1 | 58 ± 3 | 1100 ± 76 | 3053 ± 15 | >200,000 | >200,000 |
