TABLE 1.
Classification of changes in CEF gene expression following infection with the very virulent RB1B strain of MDV
| Category | Gene | Fold induction in MDV-infected CEFa
|
|||
|---|---|---|---|---|---|
| Expt 1
|
Expt 2
|
||||
| 2 dpi | 4 dpi | 2 dpi | 4 dpi | ||
| Strongly induced (5-fold in both expts) | MIP | 6.9 | 2.5 | 4.6 | 4.5 |
| Quiescence-specific protein | 2.5 | 5.9 | 5.9 | 6.5 | |
| IRF-1 | 5.7 | 0.79 | 3.5 | 5.5 | |
| Moderately induced (5-fold in 1 expt; 2-fold in the other) | β2-Microglobulin | 5.0 | 5.6 | 2.3 | 4.0 |
| MHC class II | 2.2 | 2.2 | 5.3 | 8.4 | |
| Somewhat induced (3-fold in 1 expt; 2-fold in the other) | TSA-1 | 3.7 | 2.3 | 1.8 | 2.4 |
| IFN-inducible protein | 3.5 | 1.1 | 2.0 | 2.8 | |
| ALV-J | 3.0 | 1.8 | 2.1 | 2.6 | |
| Clusterin | 1.7 | 3.3 | 1.6 | 2.9 | |
| Weakly induced (2-fold in both expts) | IL-13Rα | 2.8 | 1.7 | 2.0 | 2.5 |
| MHC class I | 2.9 | 1.6 | 2.1 | 2.7 | |
| Kinase | 2.8 | 1.0 | 2.0 | 2.4 | |
| Ovotransferrin | 1.1 | 2.2 | 1.6 | 2.3 | |
a
Each value is the average of duplicate samples and is the value obtained using MDV-infected CEF RNA for hybridization divided by the value obtained using uninfected CEF RNA for hybridization.