Table 1.
Proteins detected in samples of salivary gland concretions.
| Protein ID, Trypsin Cleavage |
Protein ID, BrCN Cleavage |
Protein Name | Function |
|---|---|---|---|
| P02808|STAT_HUMAN | P02808|STAT_HUMAN | Statherin | Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts. It also modulates hydroxyapatite crystal formation on the tooth surface. |
| P02814|SMR3B_HUMAN | P02814|SMR3B_HUMAN | Submaxillary gland androgen-regulated protein 3B | Predicted to be involved in cellular response to lipopolysaccharide; negative regulation of peptidase activity; and regulation of sensory perception of pain. Located in extracellular exosome. |
| P06702|S10A9_HUMAN | P06702|S10A9_HUMAN | Protein S100-A9 (Calgranulin-B) | Calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. |
| P08311|CATG_HUMAN | P08311|CATG_HUMAN | Cathepsin G | Serine protease with trypsin- and chymotrypsin-like specificity. Also displays antibacterial activity against Gram-negative and Gram-positive bacteria independent of its protease activity. |
| P08493|MGP_HUMAN | P08493|MGP_HUMAN | Matrix Gla protein | Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. |
| P05109|S10A8_HUMAN | P05109|S10A8_HUMAN | S100A8 | Calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. |
| P12724|ECP_HUMAN | P12724|ECP_HUMAN | Eosinophil cationic protein | Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. |
| Q8NFU4|FDSCP_HUMAN | Follicular dendritic cell secreted peptide | Secreted mediator acting upon B-cells. | |
| P15515|HIS1_HUMAN | Histatin-1 | Major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). | |
| P80511|S10AC_HUMAN | Protein S100-A12 | Calcium-, zinc- and copper-binding protein, which plays a prominent role in the regulation of inflammatory processes and immune response. | |
| P02810|PRPC_HUMAN | Salivary acidic proline-rich phosphoprotein 1/2 | Highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth. | |
| P61626|LYSC_HUMAN | Lysozyme C | Bacteriolytic function. | |
| P35527|K1C9_HUMAN | Keratin, type I cytoskeletal 9 | May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly. | |
| P24158|PRTN3_HUMAN | Myeloblastin | Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV; play a role in neutrophil transendothelial migration. | |
| Immunoglobulins | Immunoglobulins | Immunoglobulins | Humoral immune response. |