Table 2.
Assessment of the strength of the relationship between genotypes and OFC incidence, adjusting for the influence of sex through stratified analysis.
| Genetic Variant | Genotype | OR with CI 95% | pM-H adj OR=1 | pWoolf homogeneity |
|---|---|---|---|---|
| rs987525 | AA | 1.86 (0.85–4.06) | 0.057 | 0.962 |
| rs987525 | AC | 1.95 (1.34–2.83) | <0.001 | 0.226 |
| rs987525 | CC | 0.46 (0.32–0.67) | <0.001 | 0.296 |
| rs590223 | AA | 1.04 (0.71–1.52) | 0.428 | 0.391 |
| rs590223 | AG | 0.85 (0.58–1.25) | 0.209 | 0.388 |
| rs590223 | GG | 1.44 (0.75–2.75) | 0.137 | 0.899 |
| rs522616 | AA | 0.86 (0.58–1.26) | 0.213 | 0.694 |
| rs522616 | AG | 1.23 (0.83–1.82) | 0.151 | 0.647 |
| rs522616 | GG | 0.77 (0.28–2.10) | 0.307 | 0.869 |
| rs4714384 | CC | 1.30 (0.72–2.36) | 0.194 | 0.338 |
| rs4714384 | CT | 0.66 (0.46–0.94) | 0.011 | 0.573 |
| rs4714384 | TT | 1.39 (0.97–1.98) | 0.051 | 0.300 |
Note: Incidence OR—the outcome incidence odds ratio with a confidence interval of 95% among the exposed outcome incidence to those among the unexposed after accounting for confounding; pM-H adj OR=1—the p-value of test for equality of Mantel–Haenszel adjusted OR to 1; pWoolf homogeneity—the p-value of Woolf test homogeneity of the strata OR.