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. 2024 Aug 30;25(17):9421. doi: 10.3390/ijms25179421

Figure 2.

Figure 2

The effects of anti-infective treatment in 13 patients with periodontitis on (A) the aMMP-8 POCT (ng/mL) (ORALyzer), (B) the MMP-8 activity assay (RFU per minute), (C) total MMP-8 (ng/mL) R&D systems ELISA, (D) MPO (ng/mL), (E) PMN elastase (ng/mL), (F) TIMP-1 (ng/mL), (G) calprotectin (ng/mL), and (H) IL-6 (pg/mL) vs. levels in 13 healthy controls. The patients were examined at baseline visit t0 and at 1st recall visit t1 (6 weeks). The differences in the clinical parameters between t0 and t1 were tested with a paired-samples t-test (2-sided), (A) p < 0.001, (B) p = 0.002, (C) p = 0.034, (D) p < 0.001, (E) p = 0.505, (F) p = 0.055, (G) p = 0.052, and (H) p = 0.421, and between healthy controls and t0 and t1 (t-test, Bonferroni corrected), (A) p < 0.001 and p = 0.154, (B) p < 0.001 and p < 0.001, (C) p = 0.007 and p = 0.055, (D) p < 0.001 and p = 0.022, (E) p = 0.009 and p = 0.039, (F) p = 0.038 and p = 0.560, (G) p = 0.743 and p = 0.060, and (H) p = 0.739 and p = 0.317, respectively. Asterisk (*) and circle (o) represent outliers of more than 3 times the interquartile range and between 1.5 and 3 times the interquartile range, respectively.