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. 2024 Aug 27;25(17):9267. doi: 10.3390/ijms25179267

Figure 5.

Figure 5

Galectin-1 reduces PDGF-BB-mediated clustering of PDGF-Rβ. (AD). Immunohistochemical staining for PDGF-Rβ (green) of untreated human RPE cells (A) and after incubation with 20 ng/mL PDGF-BB (B), 10 µg/mL hr-galectin-1 (C) and a combination of 20 ng/mL PDGF-BB and 10 µg/mL hr-galectin-1 (D) for 30 min. Blue, DAPI staining; scale bar, 30 µm. (E). For quantification, the fluorescent signal was analyzed and plotted as relative fluorescent signal in relation to the control group. Mean ± SEM of three independent experiments; *** p < 0.001.