Table 2.

Biomarkers of endothelial damage.

Disease	Biomarkers
Pulmonary Hypertension (PH)	ET-1, Ang-2, ADMA, IL-6, IL-8, IL-10, IL-12p70, BNP, vWF
Obstructive Sleep Apnea (OSA)	HbA1c, CRP, EPO, IL-6, IL-10, VCAM1, NO, HIF-1α, NF-kß, TNF-α
Chronic Obstructive Pulmonary Disease (EPOC)	IL-6, CRP, fibrinogen, CC16, sRAGE
Acute Respiratory Distress Syndrome (ARDS)	CRP, IL-1β, TNF-α, IL-8, TGFβ1

ADMA: asymmetric dimethylarginine; Ang: angiopoietin; BNP: brain natriuretic peptide; CC16: club cell protein 16; EPO: erythropoietin; ET-1: endothelin1; HbA1c: glycated hemoglobin A; HIF-1α: hypoxia-inducible factor 1-alpha; IL: interleukin; NF-kß: Nuclear factor kappa-light-chain-enhancer of activated B cells; NO: nitrogen oxide; CRP: C-reactive protein; Srage: soluble receptor for advanced glycation end products; TNF-α: tumor necrosis factor; VCAM1: vascular cell adhesion protein 1; vWF: von Willebrand factor [57].