Table 2.

Spearman correlations between 7-oxygenated metabolites of DHEA and the cytokine panel in all premenopausal women; n = 51: 20 controls, 12 women with IH, and 19 women with PCOS.

	7αOH-DHEA		7βOH-DHEA		7-ketoDHEA
	r	p-Value	r	p-Value	r	p-Value
IL-1ra	0.313	0.028	0.311	0.030	0.311	0.029
IL-1β	0.397	0.006	0.604	<0.0001	0.467	0.001
IL-2	0.204	0.159	0.261	0.070	0.298	0.037
IL-4	0.214	0.139	0.239	0.099	0.224	0.122
IL-5	−0.012	0.938	0.179	0.258	0.144	0.364
IL-6	0.195	0.180	0.232	0.109	0.222	0.125
IL-7	0.142	0.330	0.214	0.140	0.244	0.091
IL-8	0.076	0.605	0.100	0.494	0.137	0.349
IL-9	0.176	0.227	0.229	0.114	0.216	0.136
IL-10	0.130	0.546	0.327	0.119	0.126	0.556
IL-12(p70)	0.248	0.104	0.322	0.033	0.346	0.021
IL-13	0.298	0.038	0.378	0.007	0.366	0.010
IL-15	0.101	0.509	0.261	0.083	0.232	0.125
IL-17	0.239	0.110	0.367	0.012	0.294	0.047
Eotaxin	−0.096	0.513	−0.030	0.840	−0.103	0.480
FGF basic	0.031	0.835	0.076	0.602	0.080	0.584
GM-CSF	0.179	0.219	0.221	0.128	0.233	0.107
G-CSF	0.203	0.162	0.250	0.083	0.202	0.165
IFN-γ	0.228	0.115	0.222	0.125	0.275	0.056
IP-10	0.095	0.518	0.192	0.185	0.102	0.484
MCP-1(MCAF)	0.250	0.083	0.236	0.103	0.241	0.095
MIP-1α	0.292	0.042	0.275	0.056	0.305	0.033
MIP-1β	0.111	0.446	0.402	0.004	0.176	0.226
PDGF-BB	−0.046	0.754	0.026	0.858	−0.013	0.932
RANTES	−0.135	0.356	0.075	0.611	−0.095	0.517
TNF-α	0.159	0.276	0.181	0.214	0.215	0.138
VEGF	0.040	0.786	0.106	0.474	0.103	0.485

Abbreviations of cytokines. IL—interleukin, FGF basic—fibroblast growth factor basic, G-CSF—granulocyte colony stimulating factor, GM-CSF—granulocyte macrophage colony stimulating factor, IFN-γ—interferon γ, IP-10—interferon γ-inducible protein, 10 kDa, MCAF/MCP-1—monocyte chemotactic and activating factor, MIP-1α—macrophage inflammatory protein 1α, PDGF-BB—platelet-derived growth factor, two B subunits, RANTES—regulated on activation, normal T expressed and secreted chemokine, TNF-α—tumor necrosis factor α, VEGF—vascular endothelial growth factor. p-values lower than 0.05 are marked in bold.