Table 1.
Participant baseline characteristics.
| CsA+SoC Group | SoC Group | |
|---|---|---|
| Total N (women) | 51 | 47 |
| Female sex, n (%) | 22 (43.1) | 14 (29.8) |
| Age, mean ± SD [95% CI], median | 60.2 ± 11.7 [57.0, 63.5] 60.5 | 62.9 ± 13.0 [59.1, 66.7] 62.0 |
| Age ≥ 65, n (%) | 21 (44.7) | 21 (41.2) |
| Ethnicity, n (%) (Caucasian, Hispanic, and others) | ||
| Caucasian | 26 (51) | 32 (68) |
| Hispanic | 15 (29.4) | 11 (23.4) |
| others | 10 (19.6) | 4 (8.6) |
| BMI, mean ± SD [95% CI], median | 29.2 ± 5.7 [27.5, 30.9] 28.6 | 28.7 ± 4.1 [27.4, 30.0] 28.5 |
| BMI ≥ 30, n (%) | 16 (37.2) | 14 (34.1) |
| Smoking habit, n (%) | (3, 13, 35) | (2, 19, 26) |
| Active | 3 (5.9) | 2 (4.3) |
| Past | 13 (25.5) | 19 (40.4) |
| Never smoker | 35 (68.6) | 26 (55.3) |
| a Comorbidities, n (%) | 24 (47.1) | 29 (61.7) |
| Hypertension, n (%) | 19 (37.3) | 23 (48.9) |
| Diabetes, n (%) | 10 (19.6) | 5 (10.6) |
| Ischemic heart disease, n (%) | 1 (2.0) | 5 (10.6) |
| Active cancer, n (%) | 3 (5.9) | 1 (2.1) |
| Exposure to immunosuppressants, n (%) | 1 (2.0) | 3 (6.4) |
| COPD, n (%) | 3 (5.9) | 4 (8.5) |
| History of thromboembolic disease, n (%) | 5 (9.8) | 4 (8.5) |
| Time (days) from first symptom, mean ± SD [95% CI], median | 8.8 ± 6.9 [6.8, 10.7] 8.0 | 8.5 ± 6.4 [6.7, 10.4] 8.0 |
| Days of dyspnea, mean ± SD [95% CI], median | 4.7 ± 5.2 [2.8, 6.7] 3.0 | 4.5 ± 3.9 [3.0, 6.0] 3.0 |
| Severity according to CURB-65, mean ± SD [95% CI], median | 0.8 ± 0.9 (0.6–1.1) 1.0 | ± 0.8 (0.6–1.1) 1.0 |
a Number of participants with at least one comorbidity; BMI: body mass index; COPD: chronic obstructive pulmonary disease; CsA: cyclosporine; SoC: standard of care; CI: confidence interval; and SD: standard deviation.