Table 1.
Baseline characteristics of participants N = 11,912, NHANES, USA, 2011–2018
| Variable | Total N = 11,912 | Control group N = 11,061 | TD group N = 851 | P |
|---|---|---|---|---|
| Age, Mean(SD), Year | 39.52(11.50) | 39.13 (11.49) | 44.71 (10.42) | < 0.001 |
| Sex (%) | < 0.001 | |||
| Male | 6,040 | 5869 (53.06%) | 171 (20.09%) | |
| Female | 5,872 | 5192 (46.94%) | 680 (79.91%) | |
| Race (%) | < 0.001 | |||
| Mexican American | 1686 | 1599 (14.46%) | 87 (10.22%) | |
| Other Hispanic | 1207 | 1121 (10.13%) | 86 (10.11%) | |
| Non-Hispanic White | 4145 | 3772 (34.10%) | 373 (43.83%) | |
| Non-Hispanic Black | 2665 | 2517 (22.76%) | 148 (17.39%) | |
| Other Race | 2209 | 2052 (18.55%) | 157 (18.45%) | |
| Marital Status (%) | < 0.001 | |||
| Married | 5786 | 5327 (48.16%) | 459 (53.93%) | |
| Widowed | 163 | 152 (1.37%) | 11 (1.29%) | |
| Divorced | 1099 | 985 (8.91%) | 114 (13.40%) | |
| Separated | 428 | 386 (3.49%) | 42 (4.94%) | |
| Never married | 3104 | 2937 (26.55%) | 167 (19.62%) | |
| Living with partner | 1332 | 1274 (11.52%) | 58 (6.82%) | |
| Education Level (%) | 0.003 | |||
| Less Than 9th Grade | 719 | 688 (6.22%) | 31 (3.64%) | |
| 9-11th Grade | 1457 | 1353 (12.23%) | 104 (12.22%) | |
| High School Grad/GED or Equivalent | 2602 | 2425 (21.92%) | 177 (20.80%) | |
| Some College or AA degree | 3903 | 3633 (32.85%) | 270 (31.73%) | |
| College Graduate or above | 3231 | 2962 (26.78%) | 269 (31.61%) | |
| tMFR, Mean(SD) | 2.095 (1.061) | 1.81 (0.70–8.64) | 1.46 (0.65–6.75) | < 0.001 |
| Q1(0.65–1.38) | 2978 | 2609 (23.59%) | 369 (43.36%) | |
| Q2(1.39–1.77) | 2978 | 2766 (25.01%) | 212 (24.91%) | |
| Q3(1.78–2.42) | 2978 | 2818 (25.48%) | 160 (18.80%) | |
| Q4(2.43–8.63) | 2978 | 2868 (25.93%) | 110 (12.93%) | |
| High Blood Pressure Level(%) | < 0.001 | |||
| Yes | 2899 | 2598 (23.49%) | 301 (35.37%) | |
| No | 9013 | 8463 (76.51%) | 550 (64.63%) | |
| High Cholesterol Level (%) | < 0.001 | |||
| Yes | 2928 | 2567 (23.21%) | 361 (42.42%) | |
| No | 8930 | 8448 (76.38%) | 482 (56.64%) | |
| NA | 54 | 46 (0.42%) | 8 (0.94%) | |
| Diabetes (%) | < 0.001 | |||
| Yes | 892 | 775 (7.01%) | 117 (13.75%) | |
| No | 10,798 | 10,099 (91.30%) | 699 (82.14%) | |
| NA | 222 | 187 (1.69%) | 35 (4.11%) | |
| Smoking Status (%) | 0.11 | |||
| ≥ 100 cigarettes in life | 4718 | 4359 (39.41%) | 359 (42.19%) | |
| <100 cigarettes in life | 7194 | 6702 (60.59%) | 492 (57.81%) | |
| Alcohol Consumption Status | 0.06 | |||
| ≥ 12 drink/year | 1548 | 1448 (13.09%) | 100 (11.75%) | |
| < 12 drink/year | 8175 | 7605 (68.76%) | 570 (66.98%) | |
| NA | 2189 | 2008 (18.15%) | 181 (21.27%) | |
| Depression | < 0.001 | |||
| PHQ < 9 | 6384 | 5950 (53.79%) | 434 (51.00%) | |
| PHQ ≥ 9 | 1100 | 942 (8.52%) | 158 (18.57%) | |
| NA | 4428 | 4169 (37.69%) | 259 (30.43%) |
Continuous variables with normal distributions: means and standard deviations
Continuous variables with skewness: medians and interquartile ranges
Categorical variables: frequencies and percentages
NA: Not available