Table 2.
Variable | N | OS(%) | P value | DFS(%) | P value | ||
---|---|---|---|---|---|---|---|
5-y | 8-y | 5-y | 8-y | ||||
Age, y | 0.007 | 0.007 | |||||
≤ 40 | 44 | 84.0 | 73.8 | 72.6 | 67.5 | ||
>40 | 552 | 93.3 | 91.6 | 88.9 | 83.6 | ||
Tumor location | 0.003 | 0.021 | |||||
Outer | 402 | 93.5 | 90.2 | 88.5 | 84.7 | ||
Inner/central | 194 | 90.7 | 82.2 | 86.0 | 77.5 | ||
Histological grade | 0.418 | 0.630 | |||||
I | 13 | 100 | 100 | 100 | 100 | ||
II | 300 | 93.0 | 87.7 | 89.3 | 83.1 | ||
III | 164 | 90.2 | 86.3 | 81.7 | 79.5 | ||
Unknown | 119 | 94.1 | 88.0 | 90.7 | 82.7 | ||
ER/PR status | 0.167 | 0.806 | |||||
Positive | 483 | 93.4 | 88.7 | 88.8 | 82.8 | ||
Negative | 113 | 89.3 | 83.4 | 83.1 | 80.9 | ||
HER-2 status | 0.439 | 0.329 | |||||
Negative | 373 | 94.1 | 88.5 | 89.2 | 83.4 | ||
Positive | 151 | 89.3 | 87.2 | 86.7 | 84.3 | ||
Unknown | 72 | 91.7 | 84.7 | 81.9 | 73.7 | ||
Ki-67,% | 0.011 | 0.172 | |||||
≤ 30 | 312 | 95.5 | 90.9 | 91.3 | 84.4 | ||
>30 | 284 | 89.4 | 84.3 | 83.8 | 81.8 | ||
NRN | 0.241 | 0.258 | |||||
<10 | 14 | 78.6 | 78.6 | 78.6 | 70.7 | ||
≥ 10 | 582 | 92.9 | 87.9 | 87.9 | 82.7 | ||
LNM | 0.029 | 0.089 | |||||
1 | 351 | 95.1 | 90.8 | 89.7 | 84.8 | ||
2 | 182 | 90.0 | 83.5 | 85.6 | 78.4 | ||
3 | 63 | 85.7 | 82.1 | 82.5 | 80.7 | ||
Stagea | 0.004 | 0.005 | |||||
T1 | 275 | 95.6 | 91.0 | 92.7 | 86.4 | ||
T2 | 321 | 90.0 | 84.8 | 83.4 | 79.0 | ||
LVI | 0.054 | 0.417 | |||||
No | 381 | 93.9 | 89.9 | 89.5 | 83.5 | ||
Yes | 215 | 90.2 | 83.9 | 84.7 | 80.5 |
Abbreviations LVI: lymphovascular invasion; NRN: number of removed nodes; LNM: lymph node metastasis; ER/PR: Estrogen Receptor/Progesterone Receptor; HER-2: Human epidermal growth factor receptor 2; OS: Overall survival; DFS: Disease-free survival
aOnly including T stage