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. Author manuscript; available in PMC: 2024 Sep 13.
Published in final edited form as: Nat Genet. 2024 Apr 18;56(5):792–808. doi: 10.1038/s41588-024-01707-9

Figure 1 |. Data sources and analyses in PTSD Freeze 3.

Figure 1 |

a, Data sources of genome-wide association studies (GWAS) included in PGC-PTSD Freeze 3. Collections of contributing studies are pictured as bubble plots where each circle represents a contributing study. Circle areas are proportional to sample size and colors indicate the ancestry classification of participants (blue, EA; red, AA; purple, LAT). Arrowed lines indicate data sources being pooled together to perform GWAS meta-analyses stratified by ancestry. b, Methods applied for genetic characterization of PTSD, gene prioritization analyses, and translational applications. Abbreviations: EA, European ancestry, AA, African ancestry, LAT, Native American (Latin American) ancestry; EHR, electronic health record