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. Author manuscript; available in PMC: 2024 Sep 13.
Published in final edited form as: Nat Genet. 2024 Apr 18;56(5):792–808. doi: 10.1038/s41588-024-01707-9

Figure 2 |. GWAS meta-analyses in European and multi-ancestry individuals identify a total of 95 PTSD risk loci.

Figure 2 |

Overlaid Manhattan plots of European ancestry (EA; 137,136 cases and 1,085,746 controls) and multi-ancestry meta-analyses (150,760 cases and 1,130,173 controls), showing 81 genome-wide significant (GWS) loci for the EA (full circles) and 85 GWS loci for the multi-ancestry (hollow circles) analyses. Circle colors alternate between chromosomes, with even chromosomes colored blue and odd chromosomes colored black. The y-axis refers to −log10 P-values from two-sided z-tests for meta-analysis effect estimates. The horizontal red bar indicates the threshold for GWS associations (P < 5 × 10−8).