Table 1.
Baseline characteristics according to implantation position.
| Variable | High (ID < 3 mm) |
Optimal (ID 3–7 mm) |
Low (ID > 7 mm) |
p Value |
|---|---|---|---|---|
| n = 412 | n = 1236 | n = 169 | ||
| Age, years | 82.0 [78.0; 85.0] | 82.0 [79.0; 86.0] | 82.0 [79.0; 85.0] | 0.352 |
| Female sex, % | 225 (54.6%) | 770 (62.3%) | 116 (68.6%) | 0.001 |
| BMI, kg/m2 | 26.2 [23.8; 30.0] | 26.2 [23.6; 29.8] | 26.6 [24.2; 30.1] | 0.877 |
| EuroSCORE II, % | 2.7 [1.9; 4.6] | 3.1 [2.1; 4.8] | 3.9 [2.5; 5.8] | <0.001 |
| eGFR, mL/min/1.73 m2 | 62.0 [46.0; 79.0] | 60.0 [44.0; 77.0] | 53.0 [39.0; 69.0] | <0.001 |
| Peripheral artery disease | 47 (11.4%) | 138 (11.2%) | 27 (16.0%) | 0.267 |
| Prior stroke | 54 (13.1%) | 149 (12.1%) | 23 (13.6%) | 0.920 |
| Atrial fibrillation | 151 (36.7%) | 513 (41.5%) | 77 (45.6%) | 0.029 |
| Coronary artery disease | 227 (55.1%) | 792 (64.1%) | 112 (66.3%) | 0.001 |
| Prior coronary intervention | 138 (33.6%) | 461 (37.3%) | 69 (40.8%) | 0.076 |
| Echocardiographic data | ||||
| Left ventricular ejection fraction, % | 65.0 [59.0; 65.0] | 64.0 [55.0; 65.0] | 60.0 [50.0; 65.0] | <0.001 |
| Mean aortic valve gradient, mmHg | 44.0 [36.0; 53.0] | 41.0 [31.0; 48.0] | 37.0 [29.0; 46.0] | <0.001 |
| EOA, cm2 | 0.7 [0.6; 0.8] | 0.7 [0.6; 0.9] | 0.8 [0.6; 0.9] | 0.057 |
| Electrocardiographic data | ||||
| Right bundle branch block | 44 (10.7%) | 97 (7.9%) | 17 (10.2%) | 0.411 |
| Left bundle branch block | 48 (11.7%) | 85 (6.9%) | 14 (8.4%) | 0.029 |
| Atrioventricular block | 78 (18.9%) | 204 (16.6%) | 34 (20.5%) | 0.916 |
| MDCT data | ||||
| Annulus diameter, mm | 23.8 [22.8; 25.0] | 23.9 [22.7; 25.1] | 24.0 [22.7; 25.3] | 0.600 |
| LVOT, mm | 22.6 [21.1; 24.1] | 23.2 [21.4; 24.8] | 23.2 [22.1; 25.1] | <0.001 |
| STJ, mm | 28.5 [27.0; 30.2] | 27.7 [26.0; 29.8] | 27.5 [25.6; 29.7] | <0.001 |
| Aortic valve calcification, AU | 2723 [1930; 3756] | 2110 [1417; 3031] | 1803 [1176; 2793] | <0.001 |
| Calcification in LVOT | 47 (11.4%) | 119 (9.6%) | 19 (11.2%) | 0.636 |
| Eccentric calcification | 50 (12.2%) | 117 (9.5%) | 13 (7.7%) | 0.061 |
Abbreviations: BMI = body mass index; eGFR = estimated glomerular filtration rate; EOA = estimated (aortic valve) orifice area; LVOT = left ventricular outflow tract; STJ = sinotubular junction.