Table 5.
Differences of mean protein/Phe values between PKU severities.
| Age Group | Differences by Severities |
Difference of Mean Values between Severities | |||||
|---|---|---|---|---|---|---|---|
| Phe | Natural Protein | Protein Equivalent from Protein Substitute | |||||
| mg/Day | mg/kg/Day | g/Day | g/kg/Day | g/Day | g/kg/Day | ||
| <2 y |
HPA-cPKU
mPKU-cPKU |
+405 +83 |
−19 +7 |
+9 +2 |
+0.5 +0.3 |
−12 −5 |
−1.7 −0.5 |
| 2–5 y |
HPA-cPKU
mPKU-cPKU |
+1048 +278 |
+2 +14 |
+22 +6 |
+1.1 +0.4 |
−24 −6 |
−1.7 −0.4 |
| 6–12 y |
HPA-cPKU
mPKU-cPKU |
+1660 +527 |
+17 +14 |
+35 +11 |
+1.0 +0.4 |
−36 −14 |
−1.1 −0.4 |
| 13–18 y |
HPA-cPKU
mPKU-cPKU |
+2671 +983 |
+29 +12 |
+56 +20 |
+0.9 +0.4 |
−45 −21 |
−0.8 −0.4 |
| 19–30 y |
HPA-cPKU
mPKU-cPKU |
+1818 +859 |
+11 +9 |
+36 +17 |
+0.4 +0.3 |
−25 −15 |
−0.5 −0.2 |
| 31–40 y |
HPA-cPKU
mPKU-cPKU |
−102 +538 |
−8 +5 |
−3 +12 |
0 +0.2 |
−3 −9 |
+0.3 −0.1 |
| ≥41 y |
HPA-cPKU
mPKU-cPKU |
n/a +149 |
n/a +2 |
n/a +6 |
n/a +0.1 |
n/a −6 |
n/a −0.1 |
Abbreviations: y—years; Phe—phenylalanine; HPA—hyperphenylalaninemia; mPKU—mild PKU; cPKU—classical PKU; n/a—not available. Total protein intakes are not shown in the table as they were similar between different severities.