Table 4.
Correlation between the dysbiosis index (DI) and the severity of symptoms (S-score) and the level of tested metabolites in urine: HVA—hydroxyphenylacetic acid; 5-HIAA—5-hydroxyindoleacetic acid; PhAc—p-hydroxyphenylacetic acid; 3-IS—3-indoxyl sulfate and HVA/HIA ratio in patients with functional constipation. The correlations were analyzed using the Spearman rank test; significant values (alpha = 0.05) are marked *.
| Variable | DI | S-Score | HVA | 5-HIAA | HVA/HIAA | PhAc | 3-IS |
|---|---|---|---|---|---|---|---|
| DI | 1 | 0.68 0.00018 * |
0.17 (0.31) | −0.12 (0.44) | 0.81 0.00019 * |
−0.13 (0.42) | 0.18 (0.27) |
| S-Score | 0.68 0.00018 * |
1 | 0.20 (0.2) | 0.13 (0.93) | 0.67 0.00022 * |
−0.15 (0.35) | 0.11 (0.51) |
| HVA | 0.17 (0.31) | 0.20 (0.2) | 1 | −0.21 (0.19) | 0.33 0.034 * |
0.01 (0.97) | −0.16 (0.33) |
| 5-HIAA | −0.12 (0.44) | 0.13 (0.93) | −0.20 (0.19) | 1 | −0.11 (0.5) | 0.31 (0.052) | −0.69 (0.24) |
| HVA/HIAA | 0.81 0.00019 * |
0.67 0.00022 * |
0.33 0.034 * |
−0.11 (0.5) | 1 | −0.08 (0.62) | 0.23 (0.14) |
| PhAc | −0.13 (0.42) | −0.15 (0.35) | 0.01 (0.97) | 0.31 (0.051) | −0.08 (0.62) | 1 | −0.09 (0.59) |
| 3-IS | 0.18 (0.28) | 0.11 (0.51) | −0.16 (0.33) | −0.19 (0.24) | 0.23 (0.14) | −0.09 (0.59) | 1 |