Table 2.

The neo-clerodane-type diterpenoids isolated from Scutellaria barbata.

No.	Compound	R1	R2	R3	Reference
Type A
73	scutebata X	Nic	Bz	O	[32,42,43,44]
74	scutebata Y	Nic	Bz	β-OH, H	[43]
75	2-carbonylscutebartatin A	Nic	Nic	O	[45]
76	scutebata I	Ac	H		[42,46]
77	scutebata J	Bz	H		[47,48]
78	scutebata K	Su	H		[42,43,46,47]
79	scutebata T	Ac	De		[44,48]
80	barbatin C	H	H		[42,49,50]
81	barbatin D	Bz	Bz		[43,48,51]
82	barbatin E	Hs	Ht		[51]
83	barbatin F	Ht	Bz		[52]
84	6-O-nicotinoylbarbatin A	Nic	H		[45,53]
85	6, 7-di-O-acetoxybarbatin A	Ac	Ac		[45,49]
86	scutebarbatine A	Nic	Nic		[48,54,55,56]
87	scutebarbatine B	Nic	Bz		[50,55]
88	scutebarbatine K	Nic	Ac		[48,57]
89	scutebarbatine L	Nic	Hs		[43,48,55,57]
90	scutebarbatine Y	Bz	Nic		[32,48,54]
91	scutebartine F	Nic	Bz	Z(RΔ11–12)	[42,55]
92	scutebartine G	Nic	Nic	Z(RΔ11–12)	[42,55]
93	scutolide A	Ac	De	Z(RΔ11–12)	[44,48]
94	scutolide C	Bz	De		[48]
95	scutolide D	Bz	Hs		[48]
96	scutolide E	Ac	Bz		[48]
97	scutehenanine A	H	Nic		[42,53]
98	6-O-(2-carbonyl-3-methylbutanoyl)-scutehenanine A	Ht	Nic		[53]
99	6-O-acetylScutehenanine A	Ac	Nic		[42]
100	scutelinquanine C	Nic	Ht		[58]
101	barbaolide M	Ht	Mepr		[59]
102	scutebarbatolide A	Bz	Ac		[60]
103	scutebarbolide J	Su	OH		[42]
104	scutebarbolide K	OH	Su		[42]
105	8-O-nicotinoylbarbatin A				[45]
106	6-(2, 3-epoxy-2isopropyl-n-propoxyl) -barbatin C				[61]
107	scutolide B				[42,48,55]
108	scutebarbolide I				[42]
Type B
109	scutebata L	Bz	Bz	H	[46,47]
110	scutebarbatine D	Nic	Bz	OH	[62]
111	scutebarbatine O	Nic	Nic	OH	[63]
112	scutehenanine A	Bz	Bz	OH	[42,53]
113	scutebarbatine E	Nic	Bz		[62]
114	scutellone D	OH			[64,65,66]
115	scutellone E				[66]
116	scutellone F				[67,68]
117	scutellone H	OEt			[68,69]
118	scutellone I	OMe			[68]
119	scutebarbatine C				[62]
Type C
120	scutebata A	Bz	Bz	OH	[70,71]
121	scutebata B	Nic	Bz	OH	[25,54,70]
122	scutebata C	Nic	H	OH	[54,70]
123	scutebata W	Su	H	H	[42,71]
124	barbatin G	H	Nic	OH	[52]
125	scutebarbatine X	Nic	Nic	OH	[32,49,54,55]
126	scutebarbolide D	Bz	Nic	OH	[25,32,42]
127	scutebarbolide E	Bz	De	OH	[42]
128	scutolide F	Bz	H	H	[48]
129	scutolide G	Ac	De	H	[48]
130	scutolide H	Nic	De	H	[48]
131	scutolide I	Ac	Ac	H	[48]
132	scutolide J	Nic	Nic	H	[48]
133	barbatellarine B	Nic	Bz	H	[48,72]
134	scutebata M	Nic	Hs	OH	[46,55,72]
135	scutebarbatine Z	Nic	H	H	[32,55]
136	6-acetoxybarbatin C	Ac	H	OH	[73]
137	scutebarbolide A	Ac	H		[42]
138	scutebarbolide C	H	OH		[42]
139	scutebarbolide B				[42]
140	scutebarbolide F				[42]
141	scutebarbolide G				[42]
142	scutebarbolide H				[42]
143	barbaolide J	Nic	H	OH	[59]
144	barbaolide K				[59]
145	barbaolide L	Nic	Ac	H	[59]
146	scutebarbatolide B	Nic			[60]
147	scutebarbatolide C	Bz			[60]
148	scuttenline A	Nic	OB		[74]
149	scuttenline B				[74]
150	scuttenline C	Bz	H		[74]
151	scuttenline D				[74]
Type D
152	scutebata P	Bz	H	OBz(13S)	[49,70,75]
153	scutebata Q	Bz	OBz	H(13R)	[43,75]
154	scutehenanine C	Nic	H	Nic	[53]
155	scutebata N	Bz	H	Bz	[46,47]
156	barbatin B				[50]
157	barbatellarine C				[74]
158	barbatellarine D				[74]
159	barbatellarine E				[74]
160	barbatellarine F				[72,76]
161	scuterivulactone C1				[64,65]
162	scuterivulactone C2				[64,65]
163	scutellone C				[67,68]
164	scutellone G				[68,69]
165	barbatellarine A				[72]
Type E
166	scutebata D	Ac	Ac	Bz	[44,48,54,71]
167	scutebata E	Ac	Ac	MePr	[49,70,71]
168	scutebata F	Ac	Ac	Nic	[48,49,71]
169	scutebata G	Nic	Bz	Bz	[43,54,71]
170	scutebata O	Bz	H	H	[42,46,47]
171	scutebata R	Ac	Ac	De	[43,75]
172	scutebata S	Ac	De	Bz	[44]
173	scutebata V	Nic	Nic	H	[46]
174	scutebata B1	Ac	Nic	Nic	[43]
175	scutebata C1	Bz	H	Bz	[43]
176	scutebartine A	Nic	H	Bz	[55]
177	scubatine E	Ac	Bz	Bz	[70]
178	scubatine F	Bz	Ac	Bz	[70]
179	barbatine C	Ac	Ac	Nic	[42,55]
180	barbatine D	Nic	Ac	Nic	[55,71]
181	scutebatin A	Nic	Bz	Nic	[43,54,63]
182	scutebatin B	Nic	Nic	Bz	[54,63]
183	barbatin H	Ac	Nic	Nic	[48]
184	scutebarbatine W	Nic	H	OBz	[32,54,55]
185	scutebartine B	Ac	Ac	Nic	[55]
186	scutebatin C	Nic	H	Nic	[54]
187	scutebarbolide L	Ac	Ac	Ac	[42]
188	scutebartine C	Nic	Nic	H	[42,55]
189	scutebartine D	Nic	Nic	OH	[55]
190	scutolide K	Bz	Bz	H	[48,70]
191	scutolide L	Bz	Bz	OH	[48]
192	scutelinquanine D	H	Nic	H	[73]
193	scubatine D	Ac	Ac	Ac	[70]
194	barbatine A	Nic	Ac	Nic	[42,55,77]
195	barbatine B	Nic	Nic	Nic	[48,77]
196	barbatin A	Bz	H	Bz	[32,50]
197	scutebarbatine F	Nic	Ac	Ac	[32,54]
198	scutebarbatine G	H	H	Nic	[32,54,78]
199	6-O-nicotinoyl-7-O-acetylscutebarbatine G	Nic	Ac	Nic	[32,78]
200	6-O-nicotinoylscutebarbatine G	Nic	H	Nic	[32,54,55]
201	6,7-di-O-nicotinoylscutebarbatine G	Nic	Nic	Nic	[32,78]
202	scutehenanine B	Nic	H	Nic	[32,56]
203	scutebarbolide M	Ac	Ac	Ac	[42]
204	scutebata Z	Ac	Nic	H(13S)	[43,55]
205	scutebata A1	Ac	Nic	H(13R)	[43]
206	scutebartine E				[55]
207	scutebata U				[46]
208	scutehenanine H				[61]
209	barbaolide A	H	Nic	Ac	[59]
210	barbaolide B	ONic	Nic	MePr	[59]
211	barbaolide C	ONic	Ac	MePr	[59]
212	barbaolide D				[59]
213	barbaolide E	H	Ac	MePr	[59]
214	barbaolide F	Ac	MePr	H	[59]
215	barbaolide G				[59]
216	barbaolide H	Bz	Ac	OH	[59]
217	barbaolide I	Ac	Ac	ONic	[59]
218	scutellone J	Ac	H	Ac	[79]
219	scutelinquanine A	Ac	H	Nic	[58]
Type F
220	scutebata H	OH	Bz	Ac	[45,46]
221	scutebartine H	OMe	H	Nic	[55]
222	scutebartine I	H	OMe	Nic	[55]
223	scutebartine J	OH	Nic	Ac	[55]
224	scutebarbatine I	H	OEt		[57]
225	scutebarbatine J	OEt	H		[57]
226	scutellin A				[80]
Type G
227	scutebarbatine H	Nic	H		[78,81]
228	7-O-nicotinoylscutebarbatine H	Nic	Nic		[78,81]
229	scutehenanine D	Nic	Bz		[53]
Others
230	scutebarbatine M	Nic	Nic	OH	[82]
231	scutebarbatine N	Nic	Nic	CH2OH	[82]
232	scubatine A				[55,70]
233	scubatine B				[70]
234	scubatine C				[70]
235	scutelinquanine B				[58]
236	14-deoxy-11,12-didehydroandrographolide				[60]