Table 3.
Four sensitivity analysis results for the association between the risk of cognitive impairment and the ratio of dietary calcium intake at dinner versus breakfast according to different definitions of breakfast and dinner (n = 36,164) and calcium intake adjusted by energy by cox hazards regression model (n = 2,099)
| Q1 | Q2 | Q3 | Q4 | Q5 | p for trend | |
|---|---|---|---|---|---|---|
| Sensitivity analysis 1 | ||||||
| Δ | <0.62 | 0.62-0.97 | 0.98-1.51 | 1.52-3.02 | ≥3.03 | |
| Case/N | 118/420 | 131/420 | 133/419 | 119/420 | 167/420 | |
| Model 1 | 1 (ref.) | 1.08 (0.84,1.39) | 1.19 (0.92,1.52) | 1.06 (0.82,1.37) | 1.32 (1.03,1.68) | 0.047 |
| Model 2 | 1 (ref.) | 1.06 (0.83,1.37) | 1.14 (0.89,1.47) | 1.04 (0.80,1.35) | 1.35 (1.06,1.73) | 0.03 |
| Model 3 | 1 (ref.) | 1.03 (0.80,1.32) | 1.14 (0.88,1.46) | 1.02 (0.79,1.33) | 1.34 (1.05,1.72) | 0.028 |
| Sensitivity analysis 2 | ||||||
| Δ | <1.66 | 1.66-1.83 | 1.84-3.21 | 3.22-7.26 | ≥7.27 | |
| Case/N | 125/420 | 120/420 | 113/419 | 144/420 | 166/420 | |
| Model 1 | 1 (ref.) | 0.91 (0.71,1.17) | 0.84 (0.65,1.08) | 1.14 (0.89,1.45) | 1.22 (0.96,1.55) | 0.026 |
| Model 2 | 1 (ref.) | 0.93 (0.72,1.20) | 0.85 (0.65,1.09) | 1.15 (0.90,1.47) | 1.30 (1.02,1.65) | 0.009 |
| Model 3 | 1 (ref.) | 0.92 (0.72,1.19) | 0.85 (0.66,1.11) | 1.14 (0.89,1.46) | 1.32 (1.03,1.68) | 0.007 |
| Sensitivity analysis 3 | ||||||
| Δ | <0.79 | 0.79-1.20 | 1.21-1.91 | 1.92-3.58 | ≥3.59 | |
| Case/N | 108/420 | 138/420 | 115/419 | 142/420 | 165/420 | |
| Model 1 | 1 (ref.) | 1.13 (0.88,1.46) | 1.14 (0.87,1.48) | 1.24 (0.96,1.60) | 1.33 (1.04,1.70) | 0.022 |
| Model 2 | 1 (ref.) | 1.13 (0.88,1.46) | 1.11 (0.85,1.44) | 1.22 (0.94,1.57) | 1.36 (1.06,1.75) | 0.016 |
| Model 3 | 1 (ref.) | 1.11 (0.86,1.44) | 1.11 (0.85,1.44) | 1.21 (0.94,1.57) | 1.37 (1.07,1.76) | 0.012 |
| Sensitivity analysis 4 | ||||||
| Δ | <0.78 | 0.78-1.09 | 1.10-1.70 | 1.71-3.35 | ≥3.36 | |
| Case/N | 117/420 | 133/420 | 115/419 | 124/420 | 179/420 | |
| Model 1 | 1 (ref.) | 0.99 (0.77,1.27) | 0.90 (0.69,1.16) | 1.04 (0.81,1.35) | 1.54 (1.21,1.95) | <0.001 |
| Model 2 | 1 (ref.) | 0.98 (0.77,1.27) | 0.88 (0.68,1.14) | 1.01 (0.78,1.31) | 1.57 (1.23,1.99) | <0.001 |
| Model 3 | 1 (ref.) | 0.99 (0.77,1.28) | 0.89 (0.69,1.15) | 1.03 (0.80,1.33) | 1.59 (1.25,2.03) | <0.001 |
Model 1 was adjusted for age, gender, smoking status, drinking, urban index, and physical activity; Model 2 was further adjusted for total energy, carbohydrate, protein, fat, and dietary fiber; Model 3 was further adjusted for hypertension status, T2DM status, and BMI.