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[Preprint]. 2024 Sep 6:2024.02.05.579016. [Version 2] doi: 10.1101/2024.02.05.579016

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Fig. 3: — 3D reconstruction of Case 1. (A) Coronal slice of 3D reconstruction; boundaries between blocks are noticeable from uneven staining. (B) Registered MRI, LFB, and H&E histology of a block, with tissue boundaries (traced on LFB) overlaid. (C) Orthogonal view of reconstruction, which is smooth thanks to the Bayesian refinement, and avoids gaps and overlaps thanks to the regulariser. (D) Visualization of 3D landmark registration error (left); histogram of its magnitude (right); and mean ± standard deviation (bottom), compared with our previous pipeline [6]. See Extended Data for results on the other cases. The average landmark error across all cases is 0.99mm (vs 1.45 for [6]).