Extended Data Fig. 1. HDX overlays on best HDXer models of PR-B:SRC3 complexes.

HDX-MS overlays on best selected model of PR-B:SRC3 complex in both non-DNA-bound (top) and DNA-bound (bottom) states. Warmer colors (yellow, orange, red), indicate increased deuterium exchange, and cooler colors (green, blue) indicate decreased deuterium exchange. Black indicates the peptide was not found by HDX and gray indicates exchange within ±5%. Models selected by HDXer RMSE values, and visualizations made using ChimeraX 1.8.