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[Preprint]. 2024 Sep 2:rs.3.rs-4632384. [Version 1] doi: 10.21203/rs.3.rs-4632384/v1

Figure 5. TvFAP35 stabilizes ribbon PF A11 and outer junction proteins.

Figure 5.

(a) Cross-sectional view of the Tv-DMT cryo-EM map with enkurin and outer junction proteins colored. (b) 32 nm section of protofilaments A10, A11, A12, B1, and B2, along with their associated MIPs, shown with atomic models. (c) TvFAP35 monomer labeled with head (cyan), tail (blue), and kink (yellow), with helix numbers. (d) Zoomed-in view including important interactions of TvFAP35. (e) Electrostatic interactions at the MT-binding motif of TvFAP35. (f) Mixed residue interactions at the dimerization interface between TvFAP35 monomers. (g) Interactions between TvFAP35 and the helix-turn-helix (residues 140–164) of TvFAP77. (h) Residues 238–246 of TvFAP77 pass near the TvFAP35 coiled-coil. Residues 255 and after of TvFAP77, which stretch further down, are omitted for clarity.