Figure 5. Patient ensemble linear regression analysis.
Tumor mean Ktrans (a) across all patients at both V1 and V2 (n = 20) revealed a significant linear correlation between the ETM and cGAN (p < 0.0001; R2 = 0.99). Similarly, intratumoral slice-based mean Ktrans (b) and pixel-by-pixel Ktrans (c) had strong linear correlations between the ETM and cGAN with R2 = 0.99 (n = 359) and 0.98 (n = 143,640), respectively (p < 0.0001).